As we age, due to the reduction of collagen, your skin becomes thinner, reducing its ability to retain elasticity (from elastin) and moisture (hyaluronic acid). 

Collagen gives your skin shape. It makes your face glow, plump, and youthful looking.  The result of collagen loss creates fine lines known as wrinkles. Your skin appears looser from the pull of gravity.  Your cheeks look more hollowed; you look tired with eyelids sagging and bags under the eyes. Your skin starts looking dryer and rougher, with dark spots appearing.

How would you like to turn the clock back on your facial aging skin without a surgical facelift? Skin Rejuvenation Clinic in Richmond Hill, Ontario offers the latest skin rejuvenation treatments to help you look more youthful and radiant.

AAPE® (Advanced Adipose-Derived Stem Cell Protein Extract) skin serum is a safe, non-invasive treatment that can be applied in a clinical setting without downtime or discomfort as an aesthetic facial treatment.

The serum’s adipose or fat tissue content provides large numbers of mesenchymal stem cells (MSCs) which are located within the stromal vascular fraction (SVF) which contains powerful regenerative stem and stromal cells, progenitor cells, growth factors and many other powerful biologic components that work to regenerate cell growth.

  • AAPE® is the first product based on stem cell described in SCI journals with clinical results in humans.
  • Exosomes from human adipose derived stem cells promote proliferation and migration of skin fibroblasts.
  • AAPE has over 600,000 clinical treatments used by over 3,000 dermatologists in more than 30 countries worldwide.
  • In Japan, over 200 clinics are using AAPE with a clinical hair program for hair regrowth. The brand AAPE is approved by dermatologists and medical professionals from Korea, Japan and USA.
  • Adipose-derived stem cell-conditioned medium is rich in growth factors such as vascular endothelial growth factor, hepatocyte growth factor, platelet-derived growth factor, and insulin-like growth factor 1.


Numerous research papers in the hair growth field using Adipose-Derived Stem Cells. Papers related to ADSCs and hair on PubMed.

  • US FDA, CFDA Approval
  • PCPC US registration
  • 15 International SCI journals
  • 28 Patents registration worldwide


Cellexosome® therapy using AAPE plus plant-derived exosome (panax ginseng exosomes and asparagus exosomes) is gaining popularity as one of the promising areas of regenerative treatment for skin rejuvenation. Exosome is a naturally formulated nano carrier of cell signaling. Using exosome therapy, Cellexosome® is applied topically using a micro-needling device.

After application, Cellexosome® will trigger healing, cell stimulation and natural regeneration of the skin cells.